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1

Development and evaluation of a gentamicin pharmacokinetic model that facilitates opportunistic gentamicin therapeutic drug monitoring in neonates and infants.

Germovsek, Eva, Kent, Alison, Metsvaht, Tuuli, Lutsar, Irja, Klein, Nigel, Turner, Mark A, Sharland, Mike, Nielsen, Elisabet I, Heath, Paul T, Standing, Joseph F

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2016

Language:

english

File:

PDF, 1.07 MB

english, 2016

2

Impact of empiric antibiotic regimen on bowel colonization in neonates with suspected early onset sepsis

Ü. Parm, T. Metsvaht, E. Sepp, M.-L. Ilmoja, H. Pisarev, M. Pauskar, I. Lutsar

Journal:

European Journal of Clinical Microbiology & Infectious Diseases

Year:

2010

Language:

english

File:

PDF, 211 KB

english, 2010

3

Molecular epidemiology of Staphylococcus epidermidis in neonatal intensive care units

Soeorg, Hiie, Huik, Kristi, Parm, Ülle, Ilmoja, Mari-Liis, Metsvaht, Tuuli, Lutsar, Irja

Journal:

Year:

2016

Language:

english

File:

PDF, 285 KB

english, 2016

4

Pharmacokinetics of penicillin G in preterm and term neonates

Padari, Helgi, Metsvaht, Tuuli, Germovsek, Eva, Barker, Charlotte I, Kipper, Karin, Herodes, Koit, Standing, Joseph F, Oselin, Kersti, Tasa, Tõnis, Soeorg, Hiie, Lutsar, Irja

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2018

Language:

english

File:

PDF, 1.14 MB

english, 2018

5

Periventricular Venous Infarction in an Extremely Premature Infant as the Cause of Schizencephaly

Ilves, Norman, Ilves, Pilvi, Ãunap, Katrin, Laugesaar, Rael, Loorits, Dagmar, Lintrop, Mare, MÃ¤nnamaa, Mairi, Metsvaht, Tuuli

Journal:

Journal of Pediatric Neurology

Year:

2020

File:

PDF, 239 KB

2020

6

Meropenem vs standard of care for treatment of late onset sepsis in children of less than 90 days of age: study protocol for a randomised controlled trial

Irja Lutsar, Ursula MT Trafojer, Paul T Heath, Tuuli Metsvaht, Joseph Standing, Susanna Esposito, Vincent Meiffredy de Cabre, Clarissa Oeser, Jean-Pierre Aboulker, The NeoMero Consortium

Journal:

Year:

2011

Language:

english

File:

PDF, 278 KB

english, 2011

7

Drug utilisation pattern and off-label use of medicines in Estonian neonatal units

Jana Lass, Ruth Käär, Kaarin Jõgi, Heili Varendi, Tuuli Metsvaht, Irja Lutsar

Journal:

European Journal of Clinical Pharmacology

Year:

2011

Language:

english

File:

PDF, 306 KB

english, 2011

8

Ampicillin versus penicillin in the empiric therapy of extremely low-birthweight neonates at risk of early onset sepsis

Tuuli Metsvaht, Mari-Liis Ilmoja, Ülle Parm, Mirjam Merila, Lea Maipuu, Piia Müürsepp, Kadri Julge, Epp Sepp, Irja Lutsar

Journal:

Pediatrics International

Year:

2011

Language:

english

File:

PDF, 618 KB

english, 2011

9

Septic shock with disseminated microfoci in multiple organs in humans

Talvik, R., Liigant, A., Tapfer, H., Tamme, K., Metsvaht, T.

Journal:

Intensive Care Medicine

Year:

1998

Language:

english

File:

PDF, 293 KB

english, 1998

10

Risk factors associated with gut and nasopharyngeal colonization by common Gram-negative species and yeasts in neonatal intensive care units patients

Ülle Parm, Tuuli Metsvaht, Epp Sepp, Mari-Liis Ilmoja, Heti Pisarev, Merit Pauskar, Irja Lutsar

Journal:

Early Human Development

Year:

2011

Language:

english

File:

PDF, 470 KB

english, 2011

11

Mucosal surveillance cultures in predicting Gram-negative late-onset sepsis in neonatal intensive care units

Ü. Parm, T. Metsvaht, E. Sepp, M.-L. Ilmoja, H. Pisarev, M. Pauskar, I. Lutsar

Journal:

Journal of Hospital Infection

Year:

2011

Language:

english

File:

PDF, 244 KB

english, 2011

12

Cerebral blood-flow velocities in predicting outcome of asphyxiated newborn infants

P Ilves, M Lintrop, T Metsvaht, U Vaher, T Talvik

Journal:

Acta Paediatrica

Year:

2004

Language:

english

File:

PDF, 105 KB

english, 2004

13

Possible oxidative stress in healthy term newborns

T Metsvaht, P Ilves, T Talvik, K Zilmer, M Zilmer, R Talvik

Journal:

Acta Paediatrica

Year:

1999

Language:

english

File:

PDF, 34 KB

english, 1999

14

Inflicted traumatic brain injury (ITBI) or shaken baby syndrome (SBS) in Estonia

Inga Talvik, Tuuli Metsvaht, Kaja Leito, Haide Põder, Pille Kool, Marika Väli, Mare Lintrop, Anneli Kolk, Tiina Talvik

Journal:

Acta Paediatrica

Year:

2006

Language:

english

File:

PDF, 127 KB

english, 2006

15

Low cerebral blood flow velocity and head circumference in infants with severe hypoxic ischemic encephalopathy and poor outcome

Pilvi Ilves, Mare Lintrop, Inga Talvik, Külli Muug, Lea Maipuu, Tuuli Metsvaht

Journal:

Acta Paediatrica

Year:

2009

Language:

english

File:

PDF, 175 KB

english, 2009

16

Comparison of ampicillin plus gentamicin vs. penicillin plus gentamicin in empiric treatment of neonates at risk of early onset sepsis

T Metsvaht, M-L Ilmoja, Ü Parm, L Maipuu, M Merila, I Lutsar

Journal:

Acta Paediatrica

Year:

2010

Language:

english

File:

PDF, 600 KB

english, 2010

17

Aortic Arch Thrombosis in a Neonate With Heterozygous Carrier Status of Factor V Leiden Mutation

Tuuli Metsvaht, Toomas Hermlin, Hartmut Kern, Tiina Kahre, Joel Starkopf

Journal:

Congenital Heart Disease

Year:

2006

Language:

english

File:

PDF, 104 KB

english, 2006

18

Clinical parameters predicting failure of empirical antibacterial therapy in early onset neonatal sepsis, identified by classification and regression tree analysis

Tuuli Metsvaht, Heti Pisarev, Mari-Liis Ilmoja, Ülle Parm, Lea Maipuu, Mirjam Merila, Piia Müürsepp, Irja Lutsar

Journal:

Year:

2009

Language:

english

File:

PDF, 270 KB

english, 2009

19

Prolonged outbreak ofSerratia marcescensin Tartu University Hospital: a case–control study

Vivika Adamson, Piret Mitt, Heti Pisarev, Tuuli Metsvaht, Kaidi Telling, Paul Naaber, Matti Maimets

Journal:

BMC Infectious Diseases

Year:

2012

Language:

english

File:

PDF, 238 KB

english, 2012

20

Clinical trials in neonatal sepsis

Oeser, C., Lutsar, I., Metsvaht, T., Turner, M. A., Heath, P. T., Sharland, M.

Journal:

Journal of Antimicrobial Chemotherapy

Year:

2013

Language:

english

File:

PDF, 280 KB

english, 2013

21

Risk assessment of neonatal excipient exposure: Lessons from food safety and other areas

Turner, M.A., Duncan, J.C., Shah, U., Metsvaht, T., Varendi, H., Nellis, G., Lutsar, I., Yakkundi, S., McElnay, J.C., Pandya, H., Mulla, H., Vaconsin, P., Storme, T., Rieutord, A., Nunn, A.J.

Journal:

Advanced Drug Delivery Reviews

Year:

2014

Language:

english

File:

PDF, 604 KB

english, 2014

22

Five-year prospective surveillance of nosocomial bloodstream infections in an Estonian paediatric intensive care unit

Mitt, P., Metsvaht, T., Adamson, V., Telling, K., Naaber, P., Lutsar, I., Maimets, M.

Journal:

Journal of Hospital Infection

Year:

2014

Language:

english

File:

PDF, 92 KB

english, 2014

23

European Study of Neonatal Exposure to Excipients: An update

Turner, M.A., Duncan, J., Shah, U., Metsvaht, T., Varendi, H., Nellis, G., Lutsar, I., Vaconsin, P., Storme, T., Rieutord, A., Nunn, A.J.

Journal:

International Journal of Pharmaceutics

Year:

2013

Language:

english

File:

PDF, 60 KB

english, 2013

24

Descriptive Epidemiology of Spinal Muscular Atrophy Type I in Estonia

Vaidla, Eve, Talvik, Inga, Kulla, Andres, Kahre, Tiina, Hamarik, Malle, Napa, Aita, Metsvaht, Tuuli, Piirsoo, Andres, Talvik, Tiina

Journal:

Neuroepidemiology

Year:

2006

Language:

english

File:

PDF, 122 KB

english, 2006

25

Treatment option for sepsis in children in the era of antibiotic resistance

Lutsar, Irja, Telling, Kaidi, Metsvaht, Tuuli

Journal:

Expert Review of Anti-infective Therapy

Year:

2014

Language:

english

File:

PDF, 505 KB

english, 2014

26

Pharmacokinetics of doripenem during high volume hemodiafiltration in patients with septic shock

Tamme, Kadri, Oselin, Kersti, Kipper, Karin, Low, Kaywei, Standing, Joseph F., Metsvaht, Tuuli, Karjagin, Juri, Herodes, Koit, Kern, Hartmut, Starkopf, Joel

Journal:

Journal of Clinical Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.28 MB

english, 2015

27

In vitro synergy of oxacillin and gentamicin against coagulase-negative staphylococci from blood cultures of neonates with late-onset sepsis

Brilene, Tatjana, Soeorg, Hiie, Kiis, Merilin, Sepp, Epp, Kõljalg, Siiri, Lõivukene, Krista, Jürna-Ellam, Marika, Kalinina, Jelena, Štšepetova, Jelena, Metsvaht, Tuuli, Lutsar, Irja

Journal:

Year:

2013

Language:

english

File:

PDF, 92 KB

english, 2013

28

The development of gut microbiota in critically ill extremely low birth weight infants assessed with 16S rRNA gene based sequencing

Drell, Tiina, Lutsar, Irja, Štšepetova, Jelena, Parm, Ülle, Metsvaht, Tuuli, Ilmoja, Mari-Liis, Simm, Jaak, Sepp, Epp

Journal:

Year:

2014

Language:

english

File:

PDF, 1.45 MB

english, 2014

29

Prenatal Cushing's Syndrome Secondary to Nodular Adrenocortical Hyperplasia with Unsuppressed Plasma ACTH Levels

Tillmann, V., Mägi, M.-L., Metsvaht, T.

Journal:

Journal of Pediatric Endocrinology and Metabolism

Year:

2005

Language:

english

File:

PDF, 945 KB

english, 2005

30

Short versus Long Infusion of Meropenem in Very-Low-Birth-Weight Neonates

Padari, H., Metsvaht, T., Korgvee, L.-T., Germovsek, E., Ilmoja, M.-L., Kipper, K., Herodes, K., Standing, J. F., Oselin, K., Lutsar, I.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2012

Language:

english

File:

PDF, 652 KB

english, 2012

31

Pharmacokinetics of Penicillin G in Very-Low-Birth-Weight Neonates

Metsvaht, T., Oselin, K., Ilmoja, M.-L., Anier, K., Lutsar, I.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2007

Language:

english

File:

PDF, 103 KB

english, 2007

32

An Observational Study of Blood Concentrations and Kinetics of Methyl- and Propyl-Parabens in Neonates

Mulla, H., Yakkundi, S., McElnay, J., Lutsar, I., Metsvaht, T., Varendi, H., Nellis, G., Nunn, A., Duncan, J., Pandya, H., Turner, M.

Journal:

Pharmaceutical Research

Year:

2015

Language:

english

File:

PDF, 377 KB

english, 2015

33

Potentially harmful excipients in neonatal medicines: a pan-European observational study

Nellis, Georgi, Metsvaht, Tuuli, Varendi, Heili, Toompere, Karolin, Lass, Jana, Mesek, Inge, Nunn, Anthony J, Turner, Mark A, Lutsar, Irja

Journal:

Archives of Disease in Childhood

Year:

2015

Language:

english

File:

PDF, 276 KB

english, 2015

34

Possible oxidative stress in healthy term newborns

Metsvaht, T., Ilves, P., Talvik, T., Zilmer, K., Zilmer, M., Talvik, R.

Journal:

Acta Paediatrica

Year:

1999

Language:

english

File:

PDF, 38 KB

english, 1999

35

Inflicted traumatic brain injury (ITBI) or shaken baby syndrome (SBS) in Estonia

Talvik, Inga, Metsvaht, Tuuli, Leito, Kaja, Põder, Haide, Kool, Pille, Väli, Marika, Lintrop, Mare, Kolk, Anneli, Talvik, Tiina

Journal:

Acta Paediatrica

Year:

2006

Language:

english

File:

PDF, 133 KB

english, 2006

36

Blood Loss Related to Participation in Pharmacokinetic Study in Preterm Neonates

Heidmets, Lenne-Triin, Metsvaht, Tuuli, Ilmoja, Mari-Liis, Pisarev, Heti, Oselin, Kersti, Lutsar, Irja

Journal:

Year:

2011

Language:

english

File:

PDF, 109 KB

english, 2011

37

Neonatal Spinal Muscular Atrophy Type 1 With Bone Fractures and Heart Defect

Vaidla, E., Talvik, I., Kulla, A., Sibul, H., Maasalu, K., Metsvaht, T., Piirsoo, A., Talvik, T.

Journal:

Journal of Child Neurology

Year:

2007

Language:

english

File:

PDF, 510 KB

english, 2007

38

High variability in the dosing of commonly used antibiotics revealed by a Europe-wide point prevalence study: implications for research and dissemination

Metsvaht, Tuuli, Nellis, Georgi, Varendi, Heili, Nunn, Anthony J, Graham, Susan, Rieutord, Andre, Storme, Thomas, McElnay, James, Mulla, Hussain, Turner, Mark A, Lutsar, Irja

Journal:

Year:

2015

Language:

english

File:

PDF, 1.02 MB

english, 2015

39

Gut colonization by aerobic microorganisms is associated with route and type of nutrition in premature neonates

Parm, Ülle, Metsvaht, Tuuli, Ilmoja, Mari-Liis, Lutsar, Irja

Journal:

Nutrition Research

Year:

2015

Language:

english

File:

PDF, 292 KB

english, 2015

40

Acutely and Retrospectively Diagnosed Perinatal Stroke: A Population-Based Study

Laugesaar, R., Kolk, A., Tomberg, T., Metsvaht, T., Lintrop, M., Varendi, H., Talvik, T.

Journal:

Year:

2007

Language:

english

File:

PDF, 384 KB

english, 2007

41

Comment on Pharmacokinetic Studies in Neonates: The Utility of an Opportunistic Sampling Design

Standing, Joseph F., Anderson, Brian J., Holford, Nicholas H.G., Lutsar, Irja, Metsvaht, Tuuli

Journal:

Clinical Pharmacokinetics

Year:

2015

Language:

english

File:

PDF, 363 KB

english, 2015

42

Use of dried blood spots to study excipient kinetics in neonates

Yakkundi, Shirish, McElnay, James, Millership, Jeff, Mulla, Hussain, Pandya, Hitesh, Shah, Utpal, Nunn, Tony, Rieutord, Andre, Storme, Thomas, Vaconsin, Pascal, Metsvaht, Tuuli, Varendi, Heili, Nellis

Journal:

Year:

2011

Language:

english

File:

PDF, 877 KB

english, 2011

43

Product Substitution as a Way Forward in Avoiding Potentially Harmful Excipients in Neonates

Nellis, Georgi, Metsvaht, Tuuli, Varendi, Heili, Lass, Jana, Duncan, Jennifer, Nunn, Anthony J., Turner, Mark A., Lutsar, Irja

Journal:

Paediatric Drugs

Year:

2016

Language:

english

File:

PDF, 641 KB

english, 2016

44

Therapeutic plasma exchange in treatment of fulminant liver failure in children. Report on two successfully treated cases

Kikas, R., Maipuu, L., Metsvaht, T., Eerme, M., Starkopf, J.

Journal:

European Journal of Anaesthesiology

Year:

2006

Language:

english

File:

PDF, 51 KB

english, 2006

45

Severe Trauma in Estonia: 256 consecutive cases analysed and the impact on outcomes comparing two regions

Saar, S., Merioja, I., Lustenberger, T., Lepner, U., Asser, T., Metsvaht, T., Ilmoja, M. L., Kukk, L., Starkopf, J., Talving, P.

Journal:

European Journal of Trauma and Emergency Surgery

Year:

2016

Language:

english

File:

PDF, 414 KB

english, 2016

46

Pharmacokinetics and pharmacodynamics of piperacillin/tazobactam during high volume haemodiafiltration in patients with septic shock

Tamme, K., Oselin, K., Kipper, K., Tasa, T., Metsvaht, T., Karjagin, J., Herodes, K., Kern, H., Starkopf, J.

Journal:

Acta Anaesthesiologica Scandinavica

Year:

2016

Language:

english

File:

PDF, 388 KB

english, 2016

47

Response to Letter by Temesvari

Metsvaht, T., Laugesaar, R., Kolk, A., Talvik, T.

Journal:

Year:

2008

Language:

english

File:

PDF, 287 KB

english, 2008

48

Genetic Relatedness of Coagulase-negative Staphylococci From Gastrointestinal Tract and Blood of Preterm Neonates With Late-onset Sepsis

Soeorg, Hiie, Huik, Kristi, Parm, Ülle, Ilmoja, Mari-Liis, Metelskaja, Natalja, Metsvaht, Tuuli, Lutsar, Irja

Journal:

Pediatric Infectious Disease Journal

Year:

2013

Language:

english

File:

PDF, 327 KB

english, 2013

49

ABSTRACT 526

Hallik, M., Metsvaht, T., Ilmoja, M.L., Starkopf, J.

Journal:

Pediatric Critical Care Medicine

Year:

2014

Language:

english

File:

PDF, 633 KB

english, 2014

50

Understanding pharmacokinetics/pharmacodynamics in managing neonatal sepsis

Lutsar, Irja, Metsvaht, Tuuli

Journal:

Current Opinion in Infectious Diseases

Year:

2010

Language:

english

File:

PDF, 164 KB

english, 2010